Analysis of ecological and socio-economic changes was attempted in and around protected areas to provide rational policy direction and a strategy for sustainable use and management of protected areas. Out of 8 Ecosystem-and-landscape conservation areas, 12 Wetland protected areas, 20 National Parks in Korea, 6 protected areas were chosen by use of the K-Means clustering analysis. For the analysis, 23 and 31 factors for designation and release of the protected areas were chosen, respectively. The 6 protected areas chosen were Soraksan National Park, Dadohaehaesang National Park, Donggang ecosystem-and-landscape conservation area, Upo wetland protected area, and Nakdonggang estuary wetland protected area. Then, biodiversity of the 6 protected areas were appraised by use of GIS-based spatio-temporal patterns of landcover maps, environmental conservation value assessment maps, and forest type maps. Socio-economic changes of the areas were appraised based on a survey from July 16, 2012 to August 19, 2012. Three groups of local residents, experts, and government officials (total 512 people) were chosen for the survey. The results were analyzed using Likert scales.