Ⅰ. Introduction
1. The purpose of the study
o We conducted this study to analyze the current status and cases of spatial simulation methods introduced in disease epidemiology and ecology, and to develop a spatial approach suitable for disease-ecology evaluation in the future.

2. Scope of the study
o Only the spatial simulation methodology was included in the scope of study in order to analyze the probability of introduction, infection, and spread of diseases for prediction and proactive response, and to support for disease management policies. Therefore, the scope and content of the study are as follows.
ㅇInfectious disease simulation investigation of wild animals or zoonotic subjects
ㅇInvestigation of the current status of spatial analysis techniques introduced for estimating the distribution of species and disease spread
ㅇAnalysis of spatial approach methodologies applied to actual cases and studies

Ⅱ. Spatial Analysis in Ecology
1. Spatial analysis of ecosystems and biodiversity
oSpace is a concept inherent in all processes of ecology, and ecology studies the ecological operation of space in various subfields.

2. Status of research on species distribution models
oSpecies distribution model is a habitat suitability model, or ecological status model, used to predict the habitat distribution of a species by showing the relationship between environmental factors and species.

Ⅲ. Status of Disease-Ecology Simulation Model
1. Current status of disease simulation models in the ecosystem
oMaxEnt was the most frequently used method to simulate infectious diseases in an ecosyst